Most bellows globe valves are damaged not due to use during production, but rather due to mechanical compression. Although the bellows of the bellows stop valve have different elastic levels, coatings, and PTFE protective plates, all bellows stop valves have invisible wear from the outside (surface corrosion and particle adhesion caused by internal media). Therefore, in order to avoid the forced shutdown of sterile process production due to damage to the diaphragm valve, it is usually necessary to replace the bellows before the specified service life in practice. In this way, whether it is the number of mandatory replacement bellows, the resulting maintenance costs, or the downtime of the equipment, they are significantly more than PTFE bellows valves. Another advantage of bellows valves is that they can be used in almost all production processes.

Compared with corrugated pipe globe valves, corrugated pipe valves do not encounter such problems. Regardless of the structural form of the valve body of the Vesta corrugated pipe globe valve, there will be no "dead corners" when the process equipment is running without load, ensuring tight pipeline isolation. Moreover, it can be installed in the pipeline system of sterile process equipment according to different installation methods.

In the pharmaceutical manufacturing industry, aseptic process equipment consists of many horizontal and vertical pipelines. In the design of pharmaceutical equipment, due to pipeline location and technical reasons, it is necessary to install and use this corrugated pipe shut-off valve at specific locations. For example, if a corrugated pipe globe valve is installed in a vertical pipeline, it must be connected through a 90 ° bend in the same horizontal plane. The production cost of T-shaped diaphragm valves is also high. Compared with diaphragm valves with different valve body structures and shapes, corrugated pipe valves have more advantages in terms of volume and appearance, as well as connection and installation with pipelines. Due to the different structural types of the two types of globe valves, in the early stages of aseptic process equipment design, it is necessary to choose which type of globe valve should be selected for each part.

There are a large number of valves that need to be disinfected in output devices in the fields of medicine, food, and biotechnology. However, large valves, such as the Stericom series, have little use in situations where disinfection is required. Because in these process equipment, the required medium quality for transportation is becoming less and less, people almost always choose diaphragm valves for smaller flow rates. The new bellows valve has a smaller volume and can be used with different pipeline diameters, which is more advantageous than diaphragm valves in this regard.